Does Hyponatremia have a Value in the Diagnosis of Extrapulmonary Tuberculosis in HIV-1 Infected Patients in Cambodia?

Lynen, Lut; Phan, Sok; Prem Prey, Suos; Sopheak, Thai; Harwell, Joseph; Boelaert, Marleen; Koole, Olivier; Colebunders, Robert

Does Hyponatremia have a Value in the Diagnosis of Extrapulmonary Tuberculosis in HIV-1 Infected Patients in Cambodia?

Lut Lynen^{1, *}, Sok Phan², Suos Prem Prey³, Thai Sopheak², Joseph Harwell⁴, Marleen Boelaert¹, Olivier Koole¹, Robert Colebunders^{1, 5}

¹ Institute of Tropical Medicine, Antwerp, Belgium

² Sihanouk Hospital Center of HOPE, Phnom Penh, Cambodia

³ NCHADS, National Center for HIV/AIDS Dermatology and STDs

⁴ The Warren Alpert Medical School at Brown University, division of infectious diseases, departments of internal medicine and pediatrics, Brown University, Providence, Rhodes Island, USA

⁵ University of Antwerp, Antwerp, Belgium

Article Information

Identifiers and Pagination:

Year: 2017
Volume: 1
First Page: 1
Last Page: 3
Publisher ID: TOIDJ-1-1
DOI: 10.2174/1874279300701010001

Article History:

Received Date: 20/10/2007
Revision Received Date: 16/11/2007
Acceptance Date: 18/11/2007
Electronic publication date: 5/3/2017
Collection year: 2007

© 2007 Lynen et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

^* Address correspondence to this author at the Institute of Tropical Medicine, Antwerp, Belgium. E-mail: LLynen@itg.be

Hyponatremia is a frequent finding in hospitalised HIV-patients. The diagnosis of extra-pulmonary tuberculosis (EPTB) is difficult in resource-limited settings, causing delays in treatment. In this cross-sectional study based on hospital chart review in a charity hospital in Cambodia we found that hyponatremia (serum sodium ` 134 meq/L) was significantly associated with a diagnosis of EPTB in HIV-positive adults. Our findings suggest that hyponatremia in patients with advanced stage of HIV disease should trigger a diagnostic work-up for EPTB.

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RESEARCH ARTICLE

Does Hyponatremia have a Value in the Diagnosis of Extrapulmonary Tuberculosis in HIV-1 Infected Patients in Cambodia?

Article Information

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