Very Long Persistence of Botulinum Toxin B in a Patient’s Serum
Laurence Delbrassinne1, *, Valeska Laisnez2, Mieke De Weweire3, Jean Vanderpas1, Katelijne Dierick1, Sarah Denayer1, *
Botulinum toxins type A, B, E, F may induce a serious neuroparalytic illness in humans. Botulism can be transmitted via three routes: foodborne, wound and intestinal (in situ toxemia generally observed in infants and/or in immunocompromised adults) botulism.
A case of human botulism type B due to the consumption of an imported dried ham is reported. Laboratory results confirmed the diagnosis using the mouse bioassay and the qPCR method. Botulinum toxin was still detected in the serum up to 29 days after food consumption while it was not detected anymore in the faeces.
The described case highlight i) prolonged presence of BoNT B in the serum and ii) the risks related to the preparation of artisanal products as well as the importance of an efficient communication to citizens regarding preservation methods of household products.
Correspondence: Address correspondence to this author at the Sciensano, 14, J. Wystmanstreet, B-1050 Brussels, Belgium; Tel: +3226425690; E-mail: firstname.lastname@example.org