Chronic Granulomatous Disease Revealed by Multiple Cystic and Pseudo-tumoral Liver Lesions: One Case Report

Ibtissam Khattou1, *, Imane Ait Sab1, Noureddine Rada1, Aicha Bourrahouat1, Btissam Zouita2, Dounia Basraoui2, Hicham Jalal2, Mohamed Sbihi1
1 Department of pediatrics CHU Mohammed VI Marrakech, Marrakech, Morocco
2 Department of radiology CHU Mohammed VI Marrakech, Marrakech, Morocco

© 2018 Khattou et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of pediatrics, CHU Mohammed VI Marrakech, Marrakech, Morocco; Tel: +00212678672677; E-mail:


Chronic Granulomatous Disease (CGD) is a rare immunodeficiency disease described as a lack of destruction of bacteria and fungi phagocytes by neutrophils and macrophages, it is related to an abnormality of NADPH oxidase, a free radical producer of oxygen. The most common aspect of CGD at the age of one year, is an infection of the skin or bone by two bacteria called staphylococcus aureus and serratia marcescens. In this article, the authors report a case of CGD revealed by multiple cystic and pseudo-tumoral liver lesions discovered during prolonged fever.

Keywords: Chronique granulomatous disease, Hepatic abscess, Immunodeficiency, Recurrent infections, Lesions, Macrophages.