Does Hyponatremia have a Value in the Diagnosis of Extrapulmonary Tuberculosis in HIV-1 Infected Patients in Cambodia?
Lut Lynen1, *, Sok Phan2, Suos Prem Prey3, Thai Sopheak2, Joseph Harwell4, Marleen Boelaert1, Olivier Koole1, Robert Colebunders1, 5
Identifiers and Pagination:Year: 2010
First Page: 1
Last Page: 3
Publisher Id: TOIDJ-1-1
Article History:Received Date: 20/10/2007
Revision Received Date: 16/11/2007
Acceptance Date: 18/11/2007
Electronic publication date: 5/3/2010
Collection year: 2008
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Hyponatremia is a frequent finding in hospitalised HIV-patients. The diagnosis of extra-pulmonary tuberculosis (EPTB) is difficult in resource-limited settings, causing delays in treatment. In this cross-sectional study based on hospital chart review in a charity hospital in Cambodia we found that hyponatremia (serum sodium ` 134 meq/L) was significantly associated with a diagnosis of EPTB in HIV-positive adults. Our findings suggest that hyponatremia in patients with advanced stage of HIV disease should trigger a diagnostic work-up for EPTB.