A Current Perspective of Schistosomiasis in Association with Colorectal Carcinogenesis
Eshtiyag Abdalla Abdalkareem1, 2, Khoo Boon Yin1, *
Identifiers and Pagination:Year: 2019
First Page: 7
Last Page: 12
Publisher Id: TOIDJ-11-7
Article History:Received Date: 6/10/2018
Revision Received Date: 19/12/2018
Acceptance Date: 7/1/2019
Electronic publication date: 31/1/2019
Collection year: 2019
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Schistosomiasis is one of the parasitic infections that are often found in humans. More than approximately 200 million people are infected with Schistosomiasis in tropical and subtropical areas of Africa, South America and Asian countries. Literature has long been suggesting the correlation between Schistosomiasis and colorectal malignancy. There is a considerable directory supporting the etiological relation between Schistosoma japonicum infection and colorectal cancer in the Far East, however, the available data about the role of Schistosoma mansoni that can initiate the carcinogenesis of colorectal remain insignificant.
As such, more studies of this disease should be conducted comprehensively for corporate social responsibility internationally.
The present study reviewed the available data about the role of Schistosoma, including S. mansoni in association with the carcinogenesis of colorectal.
The study shows the possible evidence of epidemiology, pathology, molecules and immunopathology associated with Schistosomal infections and colorectal cancer. The infections are apparently getting little attention nor support worldwide due to the geographical barriers and some political issues because it mainly occurs in the people living in the bottom billion and happens in the endemic regions only.
The in-depth study of this infectious disease will tailor early diagnosis, novel prescription drugs and cost-effective strategies for the treatment of infectious disease colorectal cancer, and hence eradicate the disease in the endemic regions.