Aims and Scope

The Open Infectious Diseases Journal is an Open Access online journal, which publishes both original full-length and short research articles in all important areas of infectious diseases. It covers clinical, preclinical and experimental infectious diseases. research, discovery, development, and use of infectious disease therapies and interventions, including bacterial and fungal infections, viral infections (including HIV/AIDS and hepatitis), parasitological diseases, tuberculosis and other mycobacterial diseases. Articles on vaccines and devices, epidemiology, clinical diagnosis, treatment, and control of infectious diseases, drug-resistance, chronic infections, and tropical, emergent, pediatric, dermal and sexually-transmitted infectious diseases are also accepted.


The Open Infectious Diseases Journal, a peer-reviewed journal, is an important and reliable source of current information on important developments in the field. The emphasis will be on publishing quality papers rapidly and making them freely available to researchers worldwide.


Recent Articles

Nutritional Status of Patients Co-Infected with TB/HIV During Tuberculosis Treatment at Conakry-Guinea UHC

Mamadou Saliou Sow, Alioune Camara, Sidikiba Sidibé, Ibrahima Kaba, Nestor Niouma Leno, Boubacar Djelo Diallo, Ibrahima Camara, Lansana Mady Camara

Introduction:

The aim was to assess weight gain during tuberculosis treatment in patients co-infected with tuberculosis and HIV.

Methods:

Tuberculosis patients co-infected with HIV and undergoing tuberculosis treatment in the pneumophtisiology and infectious and tropical diseases departments of the CHU in Conakry were included.

Results:

562 patients were included, with a mean age of 35.6±11.3 years, and 52.5% were women. The average Body Mass Index [BMI] at baseline was 17.8 3.3 kg/m2. 71.5% of patients had a favorable result and 28.5% had an unfavorable result [death, abandonment]. Healed and lost patients gained an average of 2.6 kg and 0.1 kg respectively. Deceased patients lost an average of 3.6 kg. The weight variations of the cured patients were different from those of the deceased [p < 0.001]. A weight gain of 5% after 6 months of treatment was associated with the treatment site [OR=3.81; 95% CI 1.08 to 13.45], alcohol consumption [OR=10.33; 95% CI 1.20 to 89.16], malnutrition before treatment [OR=2.72; 95% CI 1.43 to 5.17] and the form of tuberculosis [OR=3.27; 95% CI 1.15 to 9.33].

Conclusion:

Newly diagnosed patients co-infected with TB-HIV at Conakry's CHU are often malnourished. Weight gain during treatment seems to be a reliable indicator of the overall response to treatment.


October 15, 2021
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Editor's Choice

An Uncommon Presentation of Tuberculosis with Cervical Pott’s Disease Initially Suspected as Metastatic Lung Cancer

Roberta Buso, Marcello Rattazzi, Massimo Puato, Paolo Pauletto

Cervical Pott's disease is a rare clinical condition whose diagnosis is usually delayed. We report a case of lung tuberculosis (TB) and cervical Pott’s disease mimicking a metastatic lung cancer. The patient presented with persistent cervical pain. Radiologic examinations showed the presence of a lytic lesion of C3 vertebral body, associated with spinal cord compression. A CT scan of the thorax showed a lung nodule highly suspicious for malignancy in the apical region of right lung upper lobe. Neurosurgical decompression was performed. Unexpectedly, histological analysis showed the presence of an inflammatory infiltrate suggestive for TB infection. The patient was immediately treated with antituberculous drugs. Atypical forms of spinal TB, such as cervical TB, can be misdiagnosed as primary or metastatic cancers and lead to delay of treatment initiation that could be fatal. Awareness of this uncommon TB presentation is important to prevent morbidity and mortality associated with spinal cord injury and disease dissemination.


May 17, 2013
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