RESEARCH ARTICLE


Nutritional Status of Patients Co-Infected with TB/HIV During Tuberculosis Treatment at Conakry-Guinea UHC



Mamadou Saliou Sow1, 2, 3, *, Alioune Camara3, 4, Sidikiba Sidibé4, Ibrahima Kaba1, Nestor Niouma Leno4, Boubacar Djelo Diallo5, Ibrahima Camara2, Lansana Mady Camara5
1 Department of Infectious and Tropical Diseases, University Hospital Center of Conakry, Conakry, Guinea
2 Department of Epidemiology, Guinea Infectious Disease Research and Training Center (CERFIG), University of Conakry, Conakry, Guinea
3 Faculty of Health Sciences and Techniques, African Center of Excellence for Prevention and Control of Communicable Diseases (CEA-PCMT), Gamal Abdel Nasser University, Conakry, Guinea
4 Department of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University Conakry, Guinea
5 Department of Pneumology, Conakry University Hospital Center, Conakry, Guinea


© 2021 Sow et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Department of Infectious and Tropical Diseases, University Hospital Center of Conakry, Conakry, Guinea; Mailing address 234, Tel: +224622913830; E-mail: smsaliou@gmail.com


Abstract

Introduction:

The aim was to assess weight gain during tuberculosis treatment in patients co-infected with tuberculosis and HIV.

Methods:

Tuberculosis patients co-infected with HIV and undergoing tuberculosis treatment in the pneumophtisiology and infectious and tropical diseases departments of the CHU in Conakry were included.

Results:

562 patients were included, with a mean age of 35.6±11.3 years, and 52.5% were women. The average Body Mass Index [BMI] at baseline was 17.8 3.3 kg/m2. 71.5% of patients had a favorable result and 28.5% had an unfavorable result [death, abandonment]. Healed and lost patients gained an average of 2.6 kg and 0.1 kg respectively. Deceased patients lost an average of 3.6 kg. The weight variations of the cured patients were different from those of the deceased [p < 0.001]. A weight gain of 5% after 6 months of treatment was associated with the treatment site [OR=3.81; 95% CI 1.08 to 13.45], alcohol consumption [OR=10.33; 95% CI 1.20 to 89.16], malnutrition before treatment [OR=2.72; 95% CI 1.43 to 5.17] and the form of tuberculosis [OR=3.27; 95% CI 1.15 to 9.33].

Conclusion:

Newly diagnosed patients co-infected with TB-HIV at Conakry's CHU are often malnourished. Weight gain during treatment seems to be a reliable indicator of the overall response to treatment.

Keywords: TB-HIV, Patients, Co-infection, Nutrition, Conakry, Guinea.