RESEARCH ARTICLE


Update on Antibacterial Resistance in Low-Income Countries: Factors Favoring the Emergence of Resistance



Jordi Vila*, 1, Tibor Pal*, 2
1 Department of Clinical Microbiology, Hospital Clinic, IDIBAPS, School of Medicine, University of Barcelona, Barcelona, Spain
2 Department of Microbiology and Immunology, FMHS, UAE University, Al Ain, United Arab Emirates


© 2010 Vila et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Correspondence: * Address correspondence to this author at the Department of Clinical Microbiology, Hospital Clinic, IDIBAPS, School of Medicine, University of Barcelona, Barcelona, Spain. Tel: + 971 3 7137 480; Fax: + 971 3 7671966; E-mail: tpal@uaeu.ac.ae


Abstract

Antimicrobial resistance has increased drastically in recent years in the developing countries, and it has rapidly become a leading public health concern. The prevalence of antimicrobial resistance varies greatly between and within countries and between different pathogens. However, overall a trend to the increase of the resistance to those antimicrobial agents more often used in these countries has been observed. Several factors can contribute to the rapid emergence and dissemination of antimicrobial resistance. In this paper, the current antimicrobial resistance in different microorganisms from different countries as well as the factors contributing to the emergence and spread of resistance in developing countries will be reviewed.

Keywords: Antimicrobial agents, resistance, developing countries.